A modified porogen-leaching approached was employed to fabricate highly porous, interconnected SMP scaffolds with tunable properties.
Tissue engineering is a promising, fast-growing field that combines cells, signals, and scaffolds to regenerate damaged tissues.
To develop new, functional, engineered tissues, it is becoming increasingly important to understand how cell-material interactions affect the cell mechanobiological response.
Furthermore, deployable SMP foams showed potential for use as deployable cell-based therapies to facilitate bone repair, as expanding foams were able to support osteogenic differentiation of attached stem cells.
This work demonstrates the potential of SMPs to be employed as dynamic materials to study cell-material interactions in dynamic environments and to aid in the development of functional tissue engineered constructs.